Document Type
Article
Publication Date
1-29-2025
Publication Title
Journal of Clinical Medicine
Volume
14
Issue
3
First page number:
1
Last page number:
22
Abstract
Cardiac Resynchronization Therapy (CRT) has been established as a major component of heart failure management, resulting in a significant reduction in patient morbidity and death for patients with increased QRS duration, low left ventricular ejection fraction (LVEF), and high risk of arrhythmias. The ability to synchronize both ventricles, lower heart failure hospitalizations, and optimize clinical outcomes are some of the attractive characteristics of biventricular pacing, or CRT. However, the high rate of CRT non-responders has led to the development of new modalities including leadless CRT pacemakers (CRT-P) and devices focused on conduction system pacing (CSP). This comprehensive review aims to present recent findings from CRT clinical trials and systematic reviews that have been published that will likely guide future directions in patient care.
Keywords
cardiac resynchronization therapy; cardiac physiologic pacing; conduction system pacing; heart failure; His-bundle pacing; Left bundle branch area pacing; cardiac contractility modulation
Disciplines
Cardiology | Cardiovascular Diseases
File Format
File Size
2700 KB
Language
English
Rights
IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Repository Citation
Siddiqui, A.,
Tasouli-Drakou, V.,
Ringor, M.,
DiCaro, M. V.,
Yee, B.,
Lei, K.,
Tak, T.
(2025).
Recent Advances in Cardiac Resynchronization Therapy: Current Treatment and Future Direction.
Journal of Clinical Medicine, 14(3),
1-22.
Available at:
http://dx.doi.org/10.3390/jcm14030889