Document Type
Article
Publication Date
6-27-2025
Publication Title
Biomedicines
Volume
13
Issue
7
First page number:
1
Last page number:
22
Abstract
Heart failure is a heterogeneous disorder that can lead to cardiogenic shock. Mechanical circulatory support (MCS) devices can replace the cardiac function in an attempt to bridge patients to transplant or they can serve as destination therapy to improve overall patient functionality and in turn quality of life. Currently utilized MCS devices include devices such as Left Ventricular Assist Devices (LVADs), Biventricular Assist Devices (BiVADs), Impella, Total Artificial Hearts (TAHs), and extracorporeal membrane oxygenation (ECMO). This literature review examines a range of studies, case reports, and meta-analyses to present current approaches to mechanical circulatory support (MCS), along with the challenges and limitations of existing devices, common complications, and overall survival and long-term outcomes following MCS therapy.
Keywords
heart failure; cardiogenic shock; left-ventricular assist device; Bi-ventricular assist device; impella; total artifical heart; intra-aortic balloon pump; extra-corporeal membrane oxygenation; survival rates; clinical outcomes; MCS complications; bridge to transplant; destination therapy
Disciplines
Cardiovascular System
File Format
File Size
1406 KB
Language
English
Rights
IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Repository Citation
Dugal, J. K.,
Malhi, A. S.,
Singh, Y.,
Razmi, R.,
Vance, J.,
Sharma, D.
(2025).
Advances in Mechanical Circulatory Support (MCS): Literature Review.
Biomedicines, 13(7),
1-22.
Available at:
http://dx.doi.org/10.3390/biomedicines13071580