Document Type
Article
Publication Date
5-25-2020
Publication Title
Artery Research
Volume
26
Issue
3
First page number:
180
Last page number:
182
Abstract
Severe acute inflammation, such as sepsis, disrupts autonomic nervous system function and jeopardizes blood pressure regulation [1]. Acute hypotension under normal conditions stimulates baroreceptors to restore blood pressure by activating the sympathetic nervous system to increase heart rate and vasoconstrict peripheral vasculature. Severe acute experimental inflammation (endotoxin) blunts baroreflex-mediated increases in muscle sympathetic nerve activity during reductions in blood pressure and uncouples baroreflex control of heart rate [2]. Whether mild acute inflammation alters the ability to maintain blood pressure during a hypotensive challenge is less clear.
Keywords
Acute inflammation; Blood pressure; Blood flow; LBNP
Disciplines
Cardiovascular Diseases | Diseases | Medicine and Health Sciences
File Format
File Size
457 KB
Language
English
Rights
IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Repository Citation
Schroeder, E. C.,
Hilgenkamp, T. I.,
Lefferts, W. K.,
Fernhall, B.
(2020).
Mild Acute Inflammation does not Impair Maintenance of Blood Pressure during a Hypotensive Stimulus.
Artery Research, 26(3),
180-182.
http://dx.doi.org/10.2991/artres.k.200513.001