Award Date

12-15-2025

Degree Type

Thesis

Degree Name

Master of Science (MS)

Department

Life Sciences

First Committee Member

Matthew Meiselman

Second Committee Member

Andrew Andres

Third Committee Member

Allen Gibbs

Fourth Committee Member

Mo Weng

Fifth Committee Member

Louisa Messenger

Number of Pages

84

Abstract

Arthropods are uniquely susceptible to environmental challenges. They are ectothermic, often small, and have a high surface-area-to-volume ratio, making them particularly vulnerable to environmental fluctuations. As a result, they are critically dependent on adaptive responses to the environment for survival, and so studying them therefore provides a unique opportunity to investigate basal adaptive mechanisms that may be highly conserved across animal species.

This thesis investigates the physiological and behavioral responses of Ixodes scapularis and Drosophila melanogaster to environmental conditions, respectively, light and temperature

In Ixodes, we examined circadian regulation of locomotion and arousability. Our findings indicate that ticks exhibit heightened activity and arousability during the night, suggesting a nocturnal behavioral pattern. Diurnal quiescence meets the classical definition of sleep. Nighttime wakefulness may enhance their ability to locate hosts during periods of increased host activity.

In Drosophila, we explored the mechanisms underlying reduced egg production at extreme temperatures. Utilizing a heat-sensitive ion channel (TRPA1) to activate Gal4 lines, we identified neuronal circuits that mediate metabolic suppression in response to cold. Further, RNA interference screening of thermosensitive ion channels revealed that pan-neuronal silencing of genes including Painless and TRPA1 increases egg production under heat stress, implicating these channels in physiological response to temperature. Investigations into Johnston's organ, a mechanosensory structure, suggested its involvement in regulation of reproduction.

Collectively, these studies provide insights into the adaptive mechanisms of ectothermic organisms in response to environmental conditions, displaying that for optimal success, animals must tightly control when and where energy is utilized.

Keywords

Dormancy; Drosophila; Ixodes; Sleep; Temperature

Disciplines

Animal Sciences | Biology | Life Sciences

File Format

PDF

File Size

6000 KB

Degree Grantor

University of Nevada, Las Vegas

Language

English

Rights

IN COPYRIGHT. For more information about this rights statement, please visit http://rightsstatements.org/vocab/InC/1.0/

Available for download on Tuesday, December 15, 2026


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